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    系統將于2020-11-08 09:00 - 10:00 更新維護,給您帶來的不便,敬請諒解!
    Order NO. D262907
    兔抗SPAM1多克隆抗體
    英文名 Anti-SPAM1 rabbit polyclonal antibody
    別名 HYA1; PH20; HYAL1; HYAL3; HYAL5; PH-20; SPAG15; HEL-S-96n
    相關類別 一抗 儲存 冷凍(-20℃)
    宿主 Rabbit 反應種屬 Human
    標記物 Unconjugate 克隆類型 Unconjugate
    抗原 SPAM1    
       
    編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
    D262907-0025 25 ul 現貨
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    D262907-0100 100 ul 現貨
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    D262907-0200 200 ul 現貨
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    技術規格

    Background: Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene.
    Applications: ELISA, IHC
    Name of antibody: SPAM1
    Immunogen: Synthetic peptide of human SPAM1
    Full name: sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
    Synonyms: HYA1; PH20; HYAL1; HYAL3; HYAL5; PH-20; SPAG15; HEL-S-96n
    SwissProt: P38567
    ELISA Recommended dilution: 5000-10000
    IHC positive control: Human tonsil
    IHC Recommend dilution: 25-100
    相關文檔
    Sample Application

    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D262907(SPAM1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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