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    系統將于2020-11-08 09:00 - 10:00 更新維護,給您帶來的不便,敬請諒解!
    Order NO. D220405
    兔抗CEACAM8多克隆抗體
    英文名 Anti-CEACAM8 rabbit polyclonal antibody
    別名 carcinoembryonic antigen related cell adhesion molecule 8; CD67; CGM6; CD66b; NCA-95
    相關類別 一抗 儲存 冷凍(-20℃)
    宿主 Rabbit 反應種屬 Human
    標記物 Unconjugate 克隆類型 rabbit polyclonal
    抗原 CEACAM8    
       
    編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
    D220405-0025 25 ul 現貨
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    D220405-0100 100 ul 現貨
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    D220405-0200 200 ul 現貨
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    技術規格

    Background: Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). By probing white blood cell cDNA libraries with tumor nonspecific crossreacting antigen, Arakawa et al. (1990) isolated a cDNA encoding CEACAM8, which they called NCA-W272. The deduced 349-amino acid protein contains 11 potential N-glycosylation sites and 4 cysteines expected to form 2 intramolecular disulfide linkages. It also has a signal peptide and several domains similar to those of other CEA family proteins, such as CEACAM1 (109770). Immunoblot analysis showed expression of a 70-kD protein that was reduced to a 37-kD major protein and a 34-kD minor protein in the presence of a glycosylation inhibitor.
    Applications: ELISA, WB, IHC
    Name of antibody: CEACAM8
    Immunogen: Fusion protein of human CEACAM8
    Full name: CEA cell adhesion molecule 8
    Synonyms: CD67; CGM6; CD66b; NCA-95
    SwissProt: P31997
    ELISA Recommended dilution: 5000-10000
    IHC positive control: Human cervical cancer and Human tonsil
    IHC Recommend dilution: 50-100
    WB Predicted band size: 38 kDa
    WB Positive control: A431 and HepG2 cell lysates
    WB Recommended dilution: 200-1000
    相關文檔
    Sample Application

    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D220405(CEACAM8 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D220405(CEACAM8 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 and HepG2 cell lysates, Primary antibody: D220405(CEACAM8 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes
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