DMA, DMP and DMS are water soluble, membrane permeable, homobifunctional imidoester crosslinkers. The imidoester functional group is one of the most specific acylating groups available for the modification of primary amines and has minimal cross reactivity toward other nucleophilic groups in proteins. In addition, the imidoamide reaction product does not alter the overall charge of the protein, potentially retaining the native conformation and activity of the protein.
Soluble in water. Used to crosslink membrane proteins, Reactive towards amino groups. Amidine bond retains net charge character of protein. Reaction pH: 8~10.
1 g/bottle or 250 mg/bottle
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